This Honey Ginger Whiskey Cocktail (Penicillin) recipe is one of those warm and soothing cocktails to be enjoyed during the onset of a cold or during long winter evenings or even to sip by the fire enjoying the holiday spirits to it full extent!!!

As the name suggests Penicillin which is supposed to cure a cold and the flu, right? Well, this Penicillin, Honey Ginger Whiskey Cocktail may not really substitute your flu medicines but it certainly has ingredients that soothe the cold and flu symptoms.
The best part? Its a 3-ingredient Whiskey Cocktail. 🙂 The recipe for Penicillin cocktail made with whiskey and honey ginger syrup prefect sipping during the fall or cold winter months.
If you grew up with your mom forcing that honey ginger syrup into your throat on the onset of a cold, then as a grown up you might just love this cocktail. My husband for sure does. If you are a scotch lover like him, you might enjoy Chocolate Whiskey Cake which is also a potent whiskey dessert.
Do you know, Honey & Whiskey are a thing?
And, its called a Drambuie. This is a blend of whisky, honey, herbs and spices. Drambuie is derived from the Gaelic phrase “an dram buidheach”, meaning “the drink that satisfies”
So, why it’s really called a Penicillin?
The Penicillin was originally created by the New York bartender Sam Ross in 2005. Predominantly, whiskey is the main ingredient in this recipe and the use of ginger and honey syrup makes the strong flavor of whiskey a little less overpowering.
If you are an ardent fan of whiskey ( like my husband, who is a bit if a snob when it comes to – scotch, malt, whiskey), this can be your favorite recipe as well. Truth to be told, whiskey lover or not, this is a very good cocktail. Period.
What does a Penicillin taste like?
This Honey-Ginger-Whiskey cocktail aka Penicillin cocktail tastes like a whiskey sour really. You sprinkle a bit of cinnamon and it will taste like fall too. The use of honey-ginger syrup makes the formidable taste of whiskey approachable really.
Ingredients used in Penicillin Cocktail recipe?
Whiskey – I have used a good brand of whiskey here (never out of choices when it comes to whiskey because of my husband’s affinity to the scotch and whiskey. You can replace whiskey with scotch too because I think, scotch and ginger make an absolute great combination.
Honey – I have used a local honey in this recipe. Local honey imparts that beautiful floral notes to everything that it touches
Ginger – The organic ginger tastes best. I buy my ginger in bulk from Cost co since lot of Indian recipes require ginger. If you don’t use ginger that much, then you can buy a piece of organic ginger from any store. The organic ginger gives that heated kick which is needed for this drink.
How to make Honey-Ginger Syrup?
Honey-Ginger Syrup – makes 1 cup
- 17 oz ginger, 500g (peeled and chopped)
- 1 cup honey, g 300
- 1/4 cup hot water, 60ml
- Wash, peel and grate the ginger. It’s easiest to scrape using the back of a spoon.
- In a saucepan, combine the grated ginger, honey and water.
- Boil the combination in medium-low heat for 30 minutes.
- Cool
- Strain the syrup into a clean jar. This mixture holds in the fridge for at least 1 month. If you add a splash of vodka to the syrup it could maybe last longer, but I have not tried this.

How to Make the Penicillin Cocktail
When you’ve made your two syrups, most of the work is done. Combine ginger syrup, honey syrup, lemon juice and whiskey with a few ice cubes in a shaker. Shake vigorously for 15 seconds.
Strain into your favorite whiskey glass. I do this, and then I add extra ice cubes in the drink, but that’s just me. So I am not one to judge on how you make your whiskey drinks! I also love to garnish with a rosemary sprig. It adds a nice, aromatic touch that goes wonderful with ginger and whiskey.
Relax, and enjoy all this ‘cures all’ drink has to offer.
I’m one of those that drink ginger, honey and lemon drinks all year around. They are fresh enough for Summer, and soothing enough for Winter. So I’ve also made a Ginger Lemon Iced Tea or the caffeine free Sore Throat Tea with Honey and Ginger, and if you like the Penicillin cocktail, I urge you to try those as well!
Other uses of Honey-Ginger Syrup?
Honey melts the mucus build up that blocks the breathing passage and leads to Upper respiratory tract infections. And, ginger helps to reduce inflammation of the airway. Therefore, a mix that combines both honey and ginger provides an effective natural treatment for cough and cold symptoms.
- You can add a tbsp. of it in 1 cup of water, and let it boil. If you drink this easy-to-make hot beverage twice a day, you should feel relief.
- Use the Honey-Ginger syrup in teas
- Mix with sparkling water for homemade ginger ale.
- Use the syrup to make Moscow Mule Cocktail `
Honey Ginger Whiskey Cocktail (Penicillin)
Ingredients
For Honey Ginger Syrup
- 10 oz Fresh Ginger, 400g
- 1 cup Honey 300g
- 1/4 cup Hot water, 60ml
For Penicillin Cocktail
- 2 oz Scotch/Whiskey
- 3/4 oz Fresh squeezed lemon juice
- 3/4 oz honey-ginger syrup
Instructions
How to make Honey-Ginger Syrup
- Add the honey, water, and ginger root to a pot and bring to a boil. Reduce heat and simmer for 5 minutes, then allow the syrup to cool. Strain and store in the fridge.
How to make Penicillin Cocktail
- Pour the Scotch, lemon juice, and honey-ginger syrup into a shaker. Add ice, shake, and strain into a rocks glass with ice.

This is a tasty-looking cocktail! 😀
Reblogged this on koolkosherkitchen and commented:
In response to the Daily Prompt IRRELEVANT I am sharing this delicious and extremely healthy recipe with you, Beautiful People, because it seems totally irrelevant to anything, but in reality, it isn’t: we are in the month of High Holidays when honey is always prominent on the table and in all our recipes. In fact, it is my family tradition to dip challah in hone, rather than salt, during the entire month, until the end of Simchas Torah, the very last holiday of this entire period, to ensure a sweet year full of blessings. I’d like to extend the blessings to all of you, Beautiful People! https://dailypost.wordpress.com/prompts/irrelevant/
This sounds like a delightful treat to sip this Winter. Thanks for sharing.
So pretty.
I was given a similar recipe when I lived in NYC, featuring lime juice. It chased away the chills, but it was more like a “toss it down quickly” than a “sip and enjoy.” This one sounds much better – and I’m not one bit surprised.
xx,
mgh
(Madelyn Griffith-Haynie – ADDandSoMuchMORE dot com)
ADD/EFD Coach Training Field founder; ADD Coaching co-founder
“It takes a village to educate a world!”
Looking forward to trying this 😊
Love this I will file this away for cold and flu season 😊. You and your readers may enjoy these winter cocktails
https://reallifeofanmsw.com/tag/winter-drinks
I’m gonna try this cocktail, that’s for sure!
This will surely cure what ails you! I need to make some ginger syrup and keep it on hand. I usually have Manhattans and this sounds like a tasty cocktail!
This sounds really similar to a cocktail I get at a tapas place here– I love the ginger and whiskey together!
This sounds good for me. I better have a few to test this theory out.
This is such a lovely cocktail for the winter months and a good excuse for a cocktail to soothe a scratchy throat.
Honey and ginger certainly are good for a sore throat – or just a chilly evening! Sounds delicious!
Mmmm. I love ginger simple syrup! This cocktail looks so delicious and I will surprise hubby when I make it and he’s going to be as happy as I will be, drinking it.
Now that’s my kind of flu / cold medicine! This looks and sounds delicious! YUM
This cocktail sounds amazing! Love honey and ginger “anything” and the fact that is also good for cold and flu symptoms is a plus!
My grandmother would mix honey whiskey and lemon and use that as couch syrup when I was little.
This looks like a beautiful drink to end a Fall day with. It is so pretty. Can’t wait to try it.
Reblogged this on hocuspocus13 and commented:
jinxx♦xoxo
Love it! Good job, thanks for nice cocktails 🙂
This looks deliciously good, must try, thanks for sharing it.
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I normally have my go to shot of tequila when I feel a cold coming on…you just may have just converted me! I may have to keep this post handy for a future book pairing!
Wow! I found your site through The BookWorm Drinketh. What an interesting recipe! I love ginger, and of course Scotch and Wiskey. When I first looked at the recipe I thought – that is a lot of sugar to water – but then I realized (yeah stupid) its a syrup (of course). I had to let my Chef mind kick in. This is a special drink that I will certainly try. Thank you!
Wow, that looks good… almost makes me want to catch a cold!!